Gems from past: Neuroprotective effects of Bhilawinol and Anacardic acid against Glutamate-induced excitotoxicity in PC-12 cells.
نویسندگان
چکیده
منابع مشابه
Neuroprotective effect of resveratrol against glutamate-induced excitotoxicity.
As the major neurotransmitter in the mammalian central nervous system (CNS), excessive extracellular glutamate (Glu) can activate the Glu receptors and neuronal calcium (Ca2+) overload, then produce neurotoxicity, which is a common pathway for neuronal injury or death, and is associated with acute and chronic neurodegenerative diseases. Therefore, it has been a therapeutic strategy to investiga...
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BACKGROUND Improved therapeutics aimed at ameliorating the devastating effects of neurodegenerative diseases, such as Alzheimer's disease (AD), are pertinent to help attenuate their growing prevalence worldwide. One promising avenue for such therapeutics lies in botanical medicines that have been efficaciously employed in the likes of traditional medicine doctrines for millennium. Integral to t...
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متن کاملProtective effect of adult olfactory ensheathing cells against 6-OHDA toxicity in PC-12 cells
Olfactory ensheathing cells (OEC) have been successfully used to stimulate the growth of injured fibers and to promote functional recovery within the injured adult CNS. These cells exhibit functional properties, which are known to be involved in axonal elongation. OEC express high level of growth factors including NGF, GDNF, BDNF and NT-3, which are known to play an important role in nerve rege...
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ژورنال
عنوان ژورنال: Frontiers in Human Neuroscience
سال: 2019
ISSN: 1662-5161
DOI: 10.3389/conf.fnhum.2019.229.00033